Crizonix 250mg Capsule 60’S 
Introduction
What Afanix 40MG is used for?
- It is used to treat adult patients with a specific type of cancer of the lung (non-small cell lung cancer)
Warning & Precautions
Talk to Doctor
Talk to your doctor before you take this medicine, if you:
- Are allergic to any of the other ingredients of this medicine
- Have kidney or liver problems
- Have a history of lung inflammation (interstitial lung disease)
- Have a history of eye problems such as severe dry eyes, inflammation of the transparent layer at the front of the eye (cornea) or ulcers involving the outer part of the eye
- Use contact lenses
- Have a history of heart problems
Pregnancy & Breast Feeding
- If you are pregnant, or breastfeeding think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine
Children & Adolescents
- Do not give this medicine to children or adolescents under the age of 18 years
Driving & Using Machines
- If you experience treatment-related symptoms affecting your eye sight (e.g. redness and/or irritation of the eye, dry eye, tearing, light sensitivity) or your ability to concentrate and react, it is recommended that you do not drive or use machines until the side effect disappears
Interactions
Tell your doctor if you are taking,
- Ritonavir, ketoconazole (except in shampoo), itraconazole, erythromycin, nelfinavir, saquinavir (used to treat different kinds of infections)
- Verapamil, quinidine, amiodarone (used to treat heart conditions)
- Cyclosporine A, tacrolimus (that affect your immune system)
- Carbamazepine, phenytoin, phenobarbital (used to treat seizures)
- Rifampicin (used to treat tuberculosis)
- Sulfasalazine (used to treat inflammation/ infection)
- Rosuvastatin (used for lowering cholesterol)
How to Use
- Always take this medicine exactly as your doctor has told you
- Swallow the tablet whole with a glass of water
- Do not break, chew or crush the tablet
- Take Afanix 40mg Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal.
- Diarrhea is common with Afanix 40mg Tablet and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed.
- Afanix 40mg Tablet can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight.
- Afanix 40mg Tablet can cause redness, rash, and acne. Get treatment for skin reactions as soon as you notice them.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
If you take more Afanix 40MG
- If you think you've taken too much of this medicine, contact your doctor immediately
If you forget to take Afanix 40MG
- If your next scheduled dose is due within 8 hours, skip the missed dose and take your next dose at the usual time. Then carry on taking your tablets at regular times as usual. Do not take a double dose to make up for a missed dose
If you stop taking Afanix 40MG
- Do not stop taking this medicine without consulting your doctor
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them
Common
- Eye irritation or inflammation
- Skin rash
- Mouth sores and inflammation
- Nail infection
- Decreased appetite
- Bleeding from the nose
- Nausea, vomiting
- Itching, dry skin
- Pain, redness, swelling or peeling of the skin of your hands and feet
- Increased levels of the liver enzymes (aspartate aminotransferase and alanine aminotransferase) in blood tests
- Inflammation of the lining of the bladder with burning sensations during urination and frequent, urgent need to urinate (cystitis)
- Abnormal taste sensations (dysgeusia)
- Stomach pain, indigestion, heartburn
- Muscle spasms
- Fever
Uncommon
- Inflammation of the lungs: interstitial lung disease
- Keratitis
- Inflammation of the pancreas (pancreatitis)
More Information
Storage
- Keep this medicine out of reach of children
- Store at room temperature (15-25°C)
- Do not use this medicine after the expiry date
FAQs
Q. Is Afanix an immunotherapy or chemotherapy?
Afanix is neither an immunotherapy nor a conventional chemotherapy. It belongs to kinase inhibitors class of anti-cancer medicines. It works by blocking a group of proteins. These proteins are known to be involved in the growth and spread of cancer cells. By blocking the activity of these proteins, Afanix stops the cancer cells from growing and multiplying.
Q. How long does it take for Afanix to work?
The peak levels of Afanix are reached 2-5 hours after taking it. However, it may take weeks or months to see a noticeable change in the progression of cancer. The symptoms may improve visibly, but the effectiveness of Afanix can be confirmed only after determining certain parameters.
Q. How should I take Afanix?
Afanix is taken by mouth without food, at least 1 hour before or 3 hours after meals. Swallow the complete tablet with water without crushing or breaking it. Take this medicine once daily at about the same time each day. This will make it easier to remember to take this medicine. If you have difficulty in swallowing the tablet, dissolve it in a glass of water. Do not use any other liquid instead of water. Drop the tablet into the water without crushing it and stir occasionally for up to 15 minutes until the tablet is broken up into very small particles. Drink the liquid straight away. Then refill the glass with water and drink it to make sure all medicine is taken.
Q. Does Afanix have any effect on fertility?
Afanix may decrease fertility in both men and women Therefore, if you have any concerns regarding fertility, talk to your doctor who might suggest sperm or egg preservation before starting treatment.
Q. Can Afanix be given along with chemotherapy?
There are no supporting studies to suggest that Afanix can be used along with other chemotherapy medicines. Afanix is used to treat specific type of lung cancer when the prior chemotherapy has been insufficient.
Q. Can Afanix cure lung cancer?
No,Afanix cannot cure lung cancer, but it prolongs the survival of the patient. It may also reduce the size of the tumor.
Q. What should I avoid while taking Afanix?
You should avoid sun exposure as Afanix can make your skin sensitive to the sun. You may get a severe sunburn or may develop rash or acne or it may get worsened. Therefore, use sunscreen and wear a hat before moving out in the sun. Wear clothes that cover your skin if you have to go out in the sun.
Q. Can I do something if I get diarrhea due to Afanix?
Diarrhea is a very common side effect of Afanix. Severe diarrhea can cause excessive loss of body fluids (dehydration) and kidney problems that can sometimes lead to death. Start drinking plenty of fluids at the first signs of diarrhea and contact your doctor immediately. The doctor will start the appropriate antidiarrheal treatment (e.g. loperamide) as soon as possible. The doctor may also reduce your dose or discontinue the therapy if you develop severe diarrhea.
Afanix is neither an immunotherapy nor a conventional chemotherapy. It belongs to kinase inhibitors class of anti-cancer medicines. It works by blocking a group of proteins. These proteins are known to be involved in the growth and spread of cancer cells. By blocking the activity of these proteins, Afanix stops the cancer cells from growing and multiplying.
Q. How long does it take for Afanix to work?
The peak levels of Afanix are reached 2-5 hours after taking it. However, it may take weeks or months to see a noticeable change in the progression of cancer. The symptoms may improve visibly, but the effectiveness of Afanix can be confirmed only after determining certain parameters.
Q. How should I take Afanix?
Afanix is taken by mouth without food, at least 1 hour before or 3 hours after meals. Swallow the complete tablet with water without crushing or breaking it. Take this medicine once daily at about the same time each day. This will make it easier to remember to take this medicine. If you have difficulty in swallowing the tablet, dissolve it in a glass of water. Do not use any other liquid instead of water. Drop the tablet into the water without crushing it and stir occasionally for up to 15 minutes until the tablet is broken up into very small particles. Drink the liquid straight away. Then refill the glass with water and drink it to make sure all medicine is taken.
Q. Does Afanix have any effect on fertility?
Afanix may decrease fertility in both men and women Therefore, if you have any concerns regarding fertility, talk to your doctor who might suggest sperm or egg preservation before starting treatment.
Q. Can Afanix be given along with chemotherapy?
There are no supporting studies to suggest that Afanix can be used along with other chemotherapy medicines. Afanix is used to treat specific type of lung cancer when the prior chemotherapy has been insufficient.
Q. Can Afanix cure lung cancer?
No,Afanix cannot cure lung cancer, but it prolongs the survival of the patient. It may also reduce the size of the tumor.
Q. What should I avoid while taking Afanix?
You should avoid sun exposure as Afanix can make your skin sensitive to the sun. You may get a severe sunburn or may develop rash or acne or it may get worsened. Therefore, use sunscreen and wear a hat before moving out in the sun. Wear clothes that cover your skin if you have to go out in the sun.
Q. Can I do something if I get diarrhea due to Afanix?
Diarrhea is a very common side effect of Afanix. Severe diarrhea can cause excessive loss of body fluids (dehydration) and kidney problems that can sometimes lead to death. Start drinking plenty of fluids at the first signs of diarrhea and contact your doctor immediately. The doctor will start the appropriate antidiarrheal treatment (e.g. loperamide) as soon as possible. The doctor may also reduce your dose or discontinue the therapy if you develop severe diarrhea.
Disclaimer:The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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