Crizalk 250mg Capsule 60'S

$1639.95

Shipping fee: USD $ 22.00
Manufacturer Pfizer Limited
Country of Origin AMREICA
Composition CRIZOTINIB 250MG
Packing Size 60 Capsule(s)
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Category: 
 Introduction

What is it prescribed for?

  • Non-Small Cell Lung Cancer
    This medicine is used for the treatment of patients with metastatic Non-small cell lung cancer (NSCLC) positive for anaplastic lymphoma kinase (ALK) and ROS1 fusion gene.
 Warning & Precautions

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
General warnings

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Hepatic impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Renal Impairment

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Gastrointestinal Diseases

This medicine should be used with extreme caution in patients suffering from stomach or intestine problems due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Bradycardia

This medicine may cause bradycardia (decreased heart rate) and therefore it is recommended to monitor heart rate and blood pressure regularly. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Visual loss

This medicine may cause visual loss and should be used with extreme caution in patients with visual defects or disturbances due to the risk of worsening of the patient's condition. It is recommended to perform ophthalmic tests in such patients while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or Operating machinery

Use of this medicine may cause dizziness, visual disturbances, and tiredness. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.

QT interval prolongation

This medicine should be used with extreme caution in patients who have or may develop prolongation of QT interval due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
 Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Escitalopram
  • Atazanavir
  • Amoxapine
  • Ofloxacin
  • Fluconazole
  • Cisapride

Disease interactions

  • Kidney Disease
    This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
  • Hepatic impairment
    This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
  • Lung impairment
    This medicine should be used with caution in patients with a history of interstitial lung disease presenting with acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, and fever pending diagnostic evaluation due to the increased risk of the lung toxicity. Close monitoring of lung function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Food interactions

  • Avoid consumption of grapefruit or grapefruit juice while taking this medicine since it may cause severe adverse effects. Report to your doctor, if you experience any adverse effects such as irregular heart rhythm, diarrhea, nausea, vomiting, abdominal pain, and high blood sugar, etc.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
 How to Use
  • Take this medicine in the dose and duration as advised by your doctor.
  • Do not chew, crush or break it.
  • Take it at the same time each day, with or without food.
  • Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.
  • It may cause dizziness or blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.
 Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them

Common
  • Black or tarry stools
  • Body aches or Pain
  • Cough
  • Chest pain or discomfort
  • Fever or chills
  • Headache
  • Rapid weight gain
  • Difficulty or painful urination
  • Blood in urine and stools
  • Pale skin
  • Change in taste
  •  Decreased appetite
 FAQs

How long does it take for this medicine to take effect?
The amount of time required for this medicine to show its action is not clinically established.

How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.

Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?
No habit-forming tendencies were reported.

Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

 Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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