Coxerin 250mg Tablet 60’S

$65.95

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Manufacturer Macleods Pharmaceuticals Pvt Ltd
Country of Origin INDIA
Composition Cycloserine (250mg)
Packing Size 60 Capsules
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Categories: , 
 Introduction

What is it prescribed for?

  • Tuberculosis
    This medicine is used to treat active pulmonary and extrapulmonary tuberculosis (including kidney disease) in patients who failed to respond to primary medicines such as streptomycin, rifampin, isoniazid, and ethambutol.
  • Urinary Tract Infection
    This medicine is used to treat acute urinary tract infections in patients who failed to respond with conventional therapy.
 Warning & Precautions

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Alcohol use

Excessive concurrent use of alcohol is contraindicated while on treatment with this medicine. The risk of seizures is high in patients with the history of alcoholism.

Central nervous system toxicity

This medicine should be discontinued or dose should be reduced if the patient experiences any central nervous system toxicity such as convulsions, psychosis, sleepiness, depression, confusion, headache, tremor, vertigo, etc.

Culture and sensitivity

Before initiating treatment with this medicine, cultures should be taken and the susceptibility of the organism to the medicine should be established. In tuberculous infections, sensitivity to the other anti-tuberculous agents in the regimen should also be demonstrated.

Driving and operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Laboratory tests

Close monitoring of blood levels of this medicine is necessary, especially in patients with an impaired kidney function. Blood levels of greater than 30 mg/L are associated with toxicity. The dosage adjustments should be done to keep the blood levels of this medicine below 30 mg/L to avoid the undesired outcomes.

Vitamin B12 and/or folic acid deficiency

Coxerin Capsule and other antituberculous drugs have been associated with vitamin B12 and/or folic acid deficiency, megaloblastic anemia, and sideroblastic anemia. If evidence of anemia develops during treatment, appropriate investigations and corrective treatment should be initiated.

Kidney disease

This medicine should be used with caution in patients with kidney disease due to the increased risk of adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
 Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Tramadol
  • Live cholera vaccine
  • Bupropion
  • Fluphenazine
  • Sodium biphosphate

Disease interactions

  • Colitis
    This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

  • Information not available.
Lab interactions
  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
 How to Use

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Coxerin Capsule may be taken with or without food, but it is better to take it at a fixed time.

 Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them

Common
  • Memory loss
  • Confusion
  • Insomnia (difficulty in sleeping)
  • Retching
  • Difficulty in speaking
  • Dizziness
  • Headache
  • Convulsion
  • Anemia (low number of red blood cells)
  • Stomach pain
  • Acne-like rash
  • Paresthesia (tingling or pricking sensation)
  • Numbness
  • Irritation
  • Vertigo
  • Inflammation of vein
  • Suicidal behaviors
  • Abnormal behavior
  • Sleepiness
 FAQs

How long does it take for this medicine to take effect?
The peak effect of this medicine can be observed within 4-8 hours of administration of the dose.

How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.

Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?
No habit-forming tendencies were reported.

Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

 Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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